Filter rows in df that do not startswith pattern

I have a dataframe in python, and I want to remove the rows that begins with "V10280", "V10281" or "V10282" in col "Variable".

I was thinking of something like this

a = a.loc[a['variable'].str.startswith(("V10280", "V10281", "V10282"))]

but with "not" or "!", such as

a = a.loc[a['variable'].str.startswith(!("V10280", "V10281", "V10282"))]

but this doesn’t work.

Thanks!!

>Solution :

try:

a = a.loc[~a['variable'].str.startswith(("V10280", "V10281", "V10282"))]