Get last and first n elements of a list

Need an answer where numbers to leave from the start and end can easily be adjusted.
Thanks.

This is my code:

ls = [1,2,3,4,5,6]
# desired output: [1,2,5,6]

#Tried the following:
ls[-2:2:1]

ls[2:4:-1]

# Both return empty list

>Solution :

Code:-

#   [ 0, 1, 2, 3, 4, 5]   for positive indices
lis=[ 1, 2, 3, 4, 5, 6]
#   [-6,-5,-4,-3,-2,-1]  for negative indices
# desired output: [1,2,5,6]

#Some options are
print(lis[:2]+lis[4:])
print(lis[:2]+lis[-2:])
print(lis[-6:-4]+lis[-2:])
print(lis[-6:-4]+lis[4:])

Output:-

[1, 2, 5, 6]
[1, 2, 5, 6]
[1, 2, 5, 6]
[1, 2, 5, 6]