How to remove the value not the index from list

How do I get my code to remove the value instead of removing the index?

availableNumbers= [
1, 2, 3, 4, 5, 6
]

numberOne = int(input("Choose your first number: "))
numberTwo = int(input("Choose your second number: "))

if numberOne in availableNumbers and numberTwo in availableNumbers:
del availableNumbers[numberOne: numberTwo]

print(availableNumbers)

So if 1 and 2 was inputted, 1 and 2 would be removed not 2 and 3

>Solution :

I believe the function to do so is the remove function. Code:

availableNumbers= [
1, 2, 3, 4, 5, 6
]

numberOne = int(input("Choose your first number: "))
numberTwo = int(input("Choose your second number: "))

if numberOne in availableNumbers and numberTwo in availableNumbers:
    availableNumbers.remove(numberOne)
    availableNumbers.remove(numberTwo)

print(availableNumbers)