How to run word search function for each letter of the alphabet

I have defined a function that searches a string for all 5-letter words starting with the letter I’ve specified. A text file is then created with the processed list.

I currently must run the program manually for each letter. How can I change my code so that the function will search for all letters of the alphabet one after the other and make a separate text file for each result?

import re
from pathlib import Path

# define starting letter of word search
ltr = 'm' 

# define RegEx pattern to find all 5-letter words starting with a 
certain letter 
pattern = r'\b'+ltr+r'\w{4}\b'

# define Function WordSearch: search wordlist.txt with defined RegEx 
Pattern
def WordSearch():
    # set Path to Main Text file
    file = r'C:\Users\User1\OneDrive\Documents\wordlist.txt'

    # open Main Text file and set variable 'MainText' equal to contents
    fileToOpen = Path(file)
    f = open(fileToOpen)
    MainText = f.read()

    # search all words in Main Text and make list of those that fit the 
    # RegEx pattern defined above
    slist = re.findall(pattern,MainText)

    # make set from list to eliminate duplicate entries
    slist_nd = list(set(slist))

    # turn Set into a string
    sliststr = ' '.join(slist_nd)

    # open new txt file, write string into contents
    slist_file = open(r"C:\Users\User1\OneDrive\Documents\fivelist"+ltr+".txt", "w")
    slist_file.write(sliststr)

    # close files
    f.close()
    slist_file.close()
WordSearch()

>Solution :

Here you go.

import string
letters = string.ascii_lowercase

Then you can do

for ltr in letters:
    pattern = r'\b'+ltr+r'\w{4}\b'

Note that you have to indent all forward code to be in the for loop.